Research Analyst III – Bioanalytical Chemistry

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, well help you build a career that you can feel passionate about.

Job Summary

Position is Second Shift (but Flexible)

Discipline Summary: Bioanalytical Chemistry supports the evaluations of test compounds by providing bioanalytical quantitative analysis of drug in body fluids and tissues from non-regulated and regulated studies including preclinical safety evaluations, pharmacokinetic/pharmacodynamic studies, and clinical trials. Staff participate in the development and validation of quantitative LC/MS/MS methodology, sample analysis, and interpretation and reporting of data utilizing validated hardware and software systems. This includes the development of sample extraction techniques, rapid LC separations, and employment of laboratory robotics to enhance delivery time of bioanalytical data. Staff are also knowledgeable in the application of GxPs and applicable SOPs, along with adhering to study protocols to accurately document methods, procedures, and results for inclusion into study reports and regulatory documents.

Essential Functions:

Efficiently perform and document all procedures, materials and results in compliance with applicable regulatory standards as applicable (protocols, methods, SOPs, etc.)

Demonstrate effective communication skills through informal discussions with peers, supervisor, and team

Assist with laboratory maintenance functions

Assists with laboratory support functions such as labeling and solution preparations

Independently maintain study specific inventory of consumables

Independently write both study and non-study deviations

Independently participate in process improvement initiatives as needed

Develop and maintain critical thinking, troubleshooting and time management skills aligned with needs of the operational area

Independently execute routine sample analysis studies

Independently execute method validation projects

Operate laboratory instruments with minimal oversight

Independently perform data analysis in appropriate software for a majority of analytical platforms within an operational area

Assist with minimal oversight the completion of laboratory investigations, assay troubleshooting and quality observations

Independently prepare paperwork for routine production work

Assist project lead for sample analysis and validation studies with oversight as needed and required by operational area

Assist with training of new staff members for minimal functions as needed

Performs all other related duties as assigned

Job Qualifications

Bachelors degree (BA/BS) or equivalent experience. A minimum of 2 years of working experience in a technical laboratory role.

HPLC Experience required. LC/MS/MS experience preferred.

An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above

Ability to communicate verbally and in writing at all levels inside and outside the organization

Basic familiarity with Microsoft Office Suite

Computer skills, commensurate with Essential Functions, including the ability to learn a validated system

Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts; sometime on short notice

Ability to work under specific time constraints

The pay range for this position is $27.50/hour Shift differential for 2nd shift. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.

About Microbial Solutions

Our Microbial Solutions business group has a comprehensive portfolio of endotoxin testing, microbial detection and microbial identification products and services is unlike any other, and has been purposefully designed to meet the complex and ever-changing needs of the industry. We help clients to ensure product safety and quality with easy-to-use yet robust testing solutions that satisfy regulatory requirements, support critical decision making and improve operational efficiencies.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our clients unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

At Charles River, we are passionate about our role in improving the quality of peoples lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.

Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer – all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin, veteran or disability status.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitmentUS@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.

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