Process Development Scientist I

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, well help you build a career that you can feel passionate about.

Job Summary

The Process Development Scientist I – Upstream is responsible for studying properties of mammalian cell culture, developing new assays, and exploring new methods for viral vector production within the department of Process Development. The Process Development Scientist will be expected to design and execute process development studies and experiments, and to record, analyze, and present data to relevant stakeholders. The Scientist will also participate in various cross-functional teams and technology development activities, as well as help lead technical transfer activities and manufacturing support for clinical/commercial bioprocesses. The position will include presenting at internal departmental and cross-functional meetings and the expectation of contributing to technical reports, and possibly also scientific publications, patent applications, and regulatory submissions. The Scientist must be able make detailed observations, analyze data, interpret results, and contribute to important decisions based on data. The position entails the ability to work and perform studies independently while also being able to work collectively and cooperatively in larger team and organizational environment.

Key Responsibilities and Duties:

Design and execute experiments to support process development, including gene therapy process optimization, technology development, and process modelling.

Perform analytical testing to characterize biological processes.

Perform technical transfer activities and manufacturing support for the clinical/commercial process.

Make detailed observations, analyze data, interpret results, and convey these findings effectively in laboratory documents, technical reports, and presentations.

Participate in various cross-functional teams and demonstrate a strong ability to collaborate and communicate with others.

Present at internal departmental and cross-functional meetings; may participate in/present at external scientific meetings.

Contribute to process development and tech transfer reports, and possibly also scientific publications, patents, and regulatory submissions.

Other responsibilities as needed.

Job Qualifications

Bachelors degree with 5 years of experience, Masters degree with 2 years of experience, or PhD with 0 years of experience.

Experience in biopharmaceutical, bioprocessing, analytical, and/or drug product or process development.

Ability to actively contribute to moderately complex aspects of projects.

Experience with cell culture of various scales including shaking flasks, WA VE bags, and /or XDR bioreactor vessels.

Compensation Data

The pay range for this position is $73,150 – $101,200. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.

About Biologics Testing Solutions

With more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Offering a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs. Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our clients unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of peoples lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer – all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin, veteran or disability status.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitmentUS@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.

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